Mitapivat (AG-348)

Vendor: Abmole

Type: Molecular

SKU: M9034

$172.50 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Mitapivat (AG-348) is the first-in-class, oral effective pyruvate kinase small molecule allosteric activator. Mitapivat (AG-348) is active against wild-type and various mutated PKR enzymes, and promotes healthy red blood cell generation by activating mutated PKR to increase ATP levels.
Casnumber
1260075-17-9
Formula
C24H26N4O3S
Mw
450.55
Psmiles
O=C(N1CCN(CC1)CC2CC2)C3=CC=C(N[S](=O)(=O)C4=C5N=CC=CC5=CC=C4)C=C3
Purity
>99%
Solubility
DMSO ≥ 10 mg/mL
Target synonyms
PKR-IN-1; PKM2 activator 1020; Pyrukynd； AG-348
Mitapivat (AG-348)

Mitapivat (AG-348)

$172.50 USD