MK 886

Vendor: Abmole

Type: Molecular

SKU: M3728

$163.30 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Mk-886 (L 663536) is a potent, cellular permeable, orally active inhibitor of FLAP (IC50 at 30 nM) and leukotriene biosynthesis (IC50 at 3 nM and 1.1μM in whole white blood cells and human whole blood, respectively). Mk-886 is also a non-competitive PPARα antagonist that can induce apoptosis.
Casnumber
118414-82-7
Formula
C27H34ClNO2S
Mw
472.08
Psmiles
CC(C)C1=CC=C2[N](CC3=CC=C(Cl)C=C3)C(=C(SC(C)(C)C)C2=C1)CC(C)(C)C(O)=O
Purity
>98%
Solubility
DMSO 90 mg/mL; Ethanol 5 mg/mL
Target synonyms
L-663536
MK 886

MK 886

$163.30 USD