ML171

Vendor: Abmole

Type: Molecular

SKU: M6970

$23.00 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
ML171 is a potent and selective inhibitor of NADPH-oxidase with IC50s of 0.25 μM, 5 μM, 3μM, 5 μM and 5.5 μM for NOX1, NOX2, NOX3, NOX4 and xanthine oxidase, respectively. ML171 (2-Acetylphenothiazine;2-APT) is a potent and selective NADPH oxidase 1 (Nox1) inhibitor that blocks Nox1-dependent ROS generation, with an IC50 of 0.25 μM in HEK293-Nox1 confirmatory assay.
Casnumber
6631-94-3
Formula
C14H11NOS
Mw
241.31
Psmiles
CC(=O)C1=CC=C2SC3=C(NC2=C1)C=CC=C3
Purity
98.85%
Solubility
DMSO 50 mg/mL
Target synonyms
2-Acetylphenothiazine; 2-APT
ML171

ML171

$23.00 USD