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ML364

ML364

Regular price $113.85 USD
Sale price Regular price

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
ML364 is a small molecule inhibitor of the deubiquitinase USP2 (IC50=1.1 μM, Kd=5.2 μM) with potential anticancer activity. ML364 induces an increase in cellular cyclin D1 degradation and causes cell cycle arrest. ML364 increases the levels of mitochondrial ROS and decreases in the intracellular content of ATP.
Casnumber
1991986-30-1
Formula
C24H18F3N3O3S2
Mw
517.54
Psmiles
CC1=CC=C(C=C1)[S](=O)(=O)NC2=CC(=CC=C2C(=O)NC3=NC(=CS3)C4=CC=CC=C4)C(F)(F)F
Purity
>99%
Solubility
DMSO ≥ 30 mg/mL
Target synonyms
ML-364
Technical documents

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