ML380

Vendor: Abmole

Type: Molecular

SKU: M28716

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$166.75 USD
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For research use only — not intended for clinical or diagnostic purposes.
ML380

ML380

$166.75 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
ML380 is a potent, subtype-selective, and brain-penetrant positive allosteric modulator (PAM) of M5 mAChR, with EC50s of 190 and 610 nM for human and rat M5, respectively. ML380 exhibits moderate selectivity versus the M1 and M3 mAChR subtypes. ML380 could increase the affinity of ACh for the M5 mAChR.
Casnumber
1627138-52-6
Formula
C23H25F3N4O3S
Mw
494.53
Psmiles
CCN(CC1=CC=CC=C1C(F)(F)F)C(=O)C2CCN(CC2)S(=O)(=O)C3=CC4=C(C=C3)NN=C4
Purity
≥99.0%
Solubility
DMSO 100 mg/mL (ultrasonic)
Technical documents

Documents

Coa

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