MLi-2

Vendor: Abmole

Type: Molecular

SKU: M10595

$299.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
MLi-2 is a highly potent, and selective LRRK2 kinase inhibitor with central nervous system activity. MLi-2 exhibits exceptional potency in a purified LRRK2 kinase assay in vitro (IC50 = 0.76 nM), a cellular assay monitoring dephosphorylation of LRRK2 pSer935 LRRK2 (IC50 = 1.4 nM), and a radioligand competition binding assay (IC50 = 3.4 nM).
Casnumber
1627091-47-7
Formula
C21H25N5O2
Mw
379.46
Psmiles
CC1CN(CC(C)O1)C2=CC(=NC=N2)C3=N[NH]C4=CC=C(OC5(C)CC5)C=C34
Purity
>99%
Solubility
DMSO 60 mg/mL
Target synonyms
MLi2
MLi-2

MLi-2

$299.00 USD