MLN2480

Vendor: Abmole

Type: Molecular

SKU: M2090

$241.50 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
MLN2480 is an orally active, CNS-permeable, highly selective inhibitor of type II RAF kinase that inhibits both monomeric (class I mutant) and dimeric forms of RAF and does not cause aberrant activation of the MAPK pathway caused by type I RAF inhibitors. In addition, MLN2480 inhibits the growth of tumors harboring BRAF fusions or BRAF V600 mutations and can be used in studies related to gliomas.
Casnumber
1096708-71-2
Formula
C17H12Cl2F3N7O2S
Mw
506.29
Psmiles
CC(NC(=O)C1=C(Cl)C(=NC=N1)N)C2=NC=C(S2)C(=O)NC3=NC=C(Cl)C(=C3)C(F)(F)F
Purity
>99.0%
Solubility
DMSO 10 mM
Target synonyms
BIIB-024; Tovorafenib
MLN2480

MLN2480

$241.50 USD