Mnk2 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES5625
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA;IHC
Cellular localization
[Isoform 2]: Nucleus, PML body.; [Isoform 1]: Cytoplasm.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
2872
Human swiss prot no
Q9HBH9
Immunogen
Synthesized peptide derived from the Internal region of human Mnk2.
Isotype
IgG
Observed band
51kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
MAP kinase interacting serine/threonine kinase 2(MKNK2) Homo sapiens This gene encodes a member of the calcium/calmodulin-dependent protein kinases (CAMK) Ser/Thr protein kinase family, which belongs to the protein kinase superfamily. This protein contains conserved DLG (asp-leu-gly) and ENIL (glu-asn-ile-leu) motifs, and an N-terminal polybasic region which binds importin A and the translation factor scaffold protein eukaryotic initiation factor 4G (eIF4G). This protein is one of the downstream kinases activated by mitogen-activated protein (MAP) kinases. It phosphorylates the eukaryotic initiation factor 4E (eIF4E), thus playing important roles in the initiation of mRNA translation, oncogenic transformation and malignant cell proliferation. In addition to eIF4E, this protein also interacts with von Hippel-Lindau tumor suppressor (VHL), ring-box 1 (Rbx1) and Cullin2 (Cul2), which are all components of the CBC(VHL) ubiquitin ligase E3 complex.
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Product Citations
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More Info
More Info
Mnk2 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
