Motesanib

Vendor: Abmole

Type: Molecular

SKU: M5329

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$63.25 USD
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For research use only — not intended for clinical or diagnostic purposes.
Motesanib

Motesanib

$63.25 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
Motesanib (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret.
Casnumber
453562-69-1
Formula
C22H23N5O
Mw
373.45
Psmiles
CC1(C)CNC2=CC(=CC=C12)NC(=O)C3=C(NCC4=CC=NC=C4)N=CC=C3
Purity
>99.0%
Solubility
≥ 30 mg/mL in DMSO
Target synonyms
AMG 706
Technical documents

Documents

Coa

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