N-Desethyl Sunitinib

Vendor: Abmole

Type: Molecular

SKU: M5066

$276.00 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
N-desethyl sunitinib is a major and pharmacologically active metabolite of sunitinib, which is potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor (Ki values are 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT respectively).
Casnumber
356068-97-8
Formula
C20H23FN4O2
Mw
370.42
Psmiles
CCNCCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C
Purity
>99.0%
Solubility
10 mM in DMSO
Target synonyms
SU11662
N-Desethyl Sunitinib

N-Desethyl Sunitinib

$276.00 USD