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Nazartinib

Nazartinib

Regular price $166.75 USD
Sale price Regular price

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
Nazartinib (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (L858R, ex19del) and T790M mt, with up to 60-fold selectivity over wild type (wt) EGFR in vitro.
Casnumber
1508250-71-2
Formula
C26H31ClN6O2
Mw
495.02
Psmiles
CN(C)C/C=C/C(=O)N1CCCCC(C1)[N]2C(=NC3=CC=CC(=C23)Cl)NC(=O)C4=CC(=NC=C4)C
Purity
>99.0%
Solubility
99 mg/mL in DMSO
Target synonyms
EGF816, NVS-816
Technical documents

Documents

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