NCAM-L1 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES2903
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Cell membrane ; Single-pass type I membrane protein . Cell projection, growth cone . Cell projection, axon . Cell projection, dendrite. Colocalized with SHTN1 in close apposition with actin filaments in filopodia and lamellipodia of axonalne growth cones of hippocampal neurons (By similarity). In neurons, detected predominantly in axons and cell body, weak localization to dendrites (PubMed:20621658). .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
3897
Human swiss prot no
P32004
Immunogen
The antiserum was produced against synthesized peptide derived from human CD171/N-CAML1. AA range:1147-1196
Isotype
IgG
Observed band
180kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013],
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NCAM-L1 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
