NCB-0846

Vendor: Abmole

Type: Molecular

SKU: M5279

$1,012.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
NCB-0846 is a novel, orally small-molecule Wnt inhibitor that inhibits TNIK (TRAF2 and NCK-Interacting Kinase) with an IC50 value of 21 nM. NCB-0846 blocks TGF-β signaling pathway by inhibiting SMAD2/3 phosphorylation and nuclear translocation.
Casnumber
1792999-26-8
Formula
C21H21N5O2
Mw
375.42
Psmiles
OC1CCC(CC1)OC2=CC=CC3=C2N=C(NC4=CC=C5N=C[NH]C5=C4)N=C3
Purity
100.00%
Solubility
DMSO 30 mg/mL
NCB-0846

NCB-0846

$1,012.00 USD