NE 52-QQ57

Vendor: Abmole

Type: Molecular

SKU: M10634

$345.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
NE 52-QQ57 is an orally available GPR4 antagonist with an IC50 of 70 nM. NE 52-QQ57 significantly inhibited the AGE-induced increased expression of several key inflammatory cytokines and signaling molecules, including tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, IL-6, inducible nitric oxide synthase (iNOS), nitric oxide (NO), cyclooxygenase 2 (COX2), and prostaglandin E2 (PGE2).
Casnumber
1401728-56-0
Formula
C24H28N6O
Mw
416.52
Psmiles
CCC1=N[N]2C(=CC(=NC2=C1CC3=CC=C(C=C3)C4=NN=C(O4)C5CCNCC5)C)C
Purity
>99%
Solubility
DMSO ≥ 5 mg/mL
Target synonyms
NE52QQ57
NE 52-QQ57

NE 52-QQ57

$345.00 USD