Necrostatin-1

Vendor: Abmole

Type: Molecular

SKU: M2315

$241.50 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Necrostatin-1 (NEC-1) is a potent inhibitor of necroptosis, with an EC50 of 490 nM in Jurkat cells. Necrostin-1 is the first identified RIPK1 inhibitor, EC50=182 nM, that reduces inflammation and inhibits colitis associated tumorigenesis. Necrostatin-1 (Nec-1) is also an inhibitor of IDO.
Casnumber
4311-88-0
Formula
C13H13N3OS
Mw
259.33
Psmiles
CN1C(=O)C(CC2=C[NH]C3=CC=CC=C23)NC1=S
Purity
99.62%
Solubility
DMSO 39 mg/mL
Target synonyms
Nec-1
Necrostatin-1

Necrostatin-1

$241.50 USD