Necrosulfonamide

Vendor: Abmole

Type: Molecular

SKU: M9062

$78.20 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Necrosulfonamide is a necroptosis inhibitor which selectively targeting the mixed lineage kinase domain-like protein (MLKL) with IC50 value of 124 nM in human HT-29. Necrosulfonamide prevents MLKL-RIP1-RIP3 necrosome complex from interacting with its downstream effectors.
Casnumber
1360614-48-7
Formula
C18H15N5O6S2
Mw
461.47
Psmiles
COC1=C(N[S](=O)(=O)C2=CC=C(NC(=O)\C=C\C3=CC=C(S3)[N+]([O-])=O)C=C2)N=CC=N1
Purity
>99%
Solubility
DMSO ≥ 25 mg/mL
Target synonyms
NSA
Necrosulfonamide

Necrosulfonamide

$78.20 USD