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Neladalkib

Neladalkib

Regular price $230.00 USD
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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
Neladalkib (NVL-655, ALK-IN-27) is a novel, brain-permeable, selective ALK inhibitor with antitumor activity. For Ba/F3 CLIP1-LTK cells, NVL-655 has an IC50 of 2.7 nM. Neladalkib (NVL-655, ALK-IN-27) can be used in studies related to ALK-positive non-small cell lung cancer (NSCLC).
Casnumber
2739866-40-9
Formula
C23H22ClFN6O
Mw
452.91
Psmiles
CCN1C2=C(CC3=CN(N=C3C4=C(C=C(C=C4)F)C(OC5=C(N=CC2=C5)N)C)C)C(=N1)Cl
Purity
≥99.0%
Solubility
DMSO 100 mg/mL
Target synonyms
NVL-655; ALK-IN-27
Technical documents

Documents

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