Nemorubicin

Vendor: Abmole

Type: Molecular

SKU: M27770

$276.00 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Nemorubicin (Methoxymorpholinyl doxorubicin) is a Doxorubicin derivative with potent antitumor activity. Nemorubicin is highly cytotoxic to a variety of tumor cell lines presenting a multidrug-resistant phenotype. Nemorubicin not only intercalate into the duplex DNA, but also result in significant ligands for G-quadruplex DNA segments, stabilizing their structure. Nemorubicin requirs an intact nucleotide excision repair (NER) system to exert its activity.
Casnumber
108852-90-0
Formula
C32H37NO13
Mw
643.64
Psmiles
CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N6CCOC(C6)OC)O
Purity
≥99.0%
Solubility
DMSO 65 mg/mL (ultrasonic)
Target synonyms
Methoxymorpholinyl doxorubicin; FCE 23762; PNU 152243
Nemorubicin

Nemorubicin

$276.00 USD