Neuregulin-1 SMDF rabbit pAb
Vendor: ELK Biotechnology
SKU: ES5736
Regular price
$148.00 USD
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Regular price
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
[Pro-neuregulin-1, membrane-bound isoform]: Cell membrane; Single-pass type I membrane protein. Does not seem to be active.; [Neuregulin-1]: Secreted.; [Isoform 8]: Nucleus. May be nuclear.; [Isoform 9]: Secreted. Has a signal peptide.; [Isoform 10]: Membrane; Single-pass type I membrane protein. May possess an internal uncleaved signal sequence.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
3084
Human swiss prot no
Q02297-10
Immunogen
The antiserum was produced against synthesized peptide derived from human NRG1 isoform-10. AA range:1-50
Isotype
IgG
Observed band
44kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Apr 2016],
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Documents
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Product Citations
Product Citations
More Info
More Info
Neuregulin-1 SMDF rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per

