NLRP3/AIM2-IN-3

Vendor: Abmole

Type: Molecular

SKU: M45372

$690.00 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
NLRP3/AIM2-IN-3 is a potent inhibitor that interferes with the interaction of NLRP3 or AIM2 with the bridging protein ASC and inhibits ASC oligomerization, and has different species-specific effects on NLRP3 and AIM2 inflammasome-dependent pyroptosis. In addition, NLRP3/AIM2-IN-3 inhibited LPS/nigericin-stimulated cell pyroptosis in THP-1 macrophages with an IC50 of 0.077 ± 0.008 μM.
Casnumber
1787787-60-3
Formula
C16H14N2O2
Mw
266.29
Psmiles
C1=CC(=CC(=C1)O)NC(=O)CC2=CC3=C(C=C2)C=CN3
Purity
>98.0%
Solubility
DMSO >100 mg/mL; Methanol 50 mg/mL
NLRP3/AIM2-IN-3

NLRP3/AIM2-IN-3

$690.00 USD