NMS-P118

Vendor: Abmole

Type: Molecular

SKU: M5270

$276.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
NMS-P118 is a potent, orally available, and highly selective PARP-1 inhibitor endowed with excellent ADME and pharmacokinetic profiles, showing 150-fold selectivity for PARP-1 over PARP-2 (Kd 0.009 μM vs 1.39 μM, respectively).
Casnumber
1262417-51-5
Formula
C20H24F3N3O2
Mw
395.42
Psmiles
NC(=O)C1=CC(=CC2=C1C(=O)N(C2)C3CCN(CC3)C4CCC(F)(F)CC4)F
Purity
>99.0%
Solubility
24 mg/mL in DMSO
NMS-P118

NMS-P118

$276.00 USD