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Nofazinlimab

Nofazinlimab

Regular price $207.00 USD
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THE SCIENCE, IN DETAIL

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Specifications
Bioactivity
Nofazinlimab (CS1003), which is a humanized IgG4 PD-1 mAb, bound to recombinant human, cynomolgus monkey, and mouse PD-1 with EC50 values of 0.1757, 0.2459, and 0.3664 nM, respectively. Nofazinlimab (CS1003)blocked PD-1 interaction with its ligands, dose-dependently enhanced T cell proliferation and secretion of cytokines (IL-2 and IFN-γ) to the levels comparable to Pembrolizumab. Nofazinlimab can be used for unresectable hepatocellular carcinoma (uHCC) research.
Casnumber
2377845-98-0
Purity
>98.0%
Target synonyms
CS1003
Technical documents

Documents

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