NR0B2 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES9945
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Nucleus . Cytoplasm . Colocalizes with NEUROD1 in the nucleus.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
8431
Human swiss prot no
Q15466
Immunogen
Synthesized peptide derived from human protein . at AA range: 30-110
Isotype
IgG
Observed band
28kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq, Jul 2008],
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More Info
More Info
NR0B2 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
