NR0B2 rabbit pAb

NR0B2 rabbit pAb

Item number: ES9945
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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NR0B2 rabbit pAb

NR0B2 rabbit pAb

$148.00

NR0B2 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Immunogen
Synthesized peptide derived from human protein . at AA range: 30-110
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
28kD
Geneid human
8431
Human swiss prot no
Q15466
Cellular localization
Nucleus . Cytoplasm . Colocalizes with NEUROD1 in the nucleus.
The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq, Jul 2008],

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