NSC 617145

Vendor: Abmole

Type: Molecular

SKU: M11056

$143.75 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
NSC 617145 is a selective werner syndrome helicase (WRN) helicase inhibitor,IC50 The value is 230 nM. NSC 617145 inhibit WRN ATPase and induce double-strand rupture (DSB) and chromosomal abnormalities. NSC 617145 is selective to WRN and superior to BLM, FANCJ, ChlR1, RecQ, and UvrD helicases.
Casnumber
203115-63-3
Formula
C13H10Cl4N2O4
Mw
400.04
Psmiles
CC(C)(CN1C(=O)C(=C(C1=O)Cl)Cl)CN2C(=O)C(=C(C2=O)Cl)Cl
Purity
>98%
Solubility
DMSO ≥ 10 mg/mL
NSC 617145

NSC 617145

$143.75 USD