NST-628

Vendor: Abmole

Type: Molecular

SKU: M55232

$839.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
NST-628 is a brain-permeable MAPK pathway molecule glue that inhibits RAF phosphorylation and MEK activation. NST-628 also binds RAF and prevents the formation of BRAF-CRAF and BRAF-ARAF heterodimers, effectively inhibiting the RAS-MAPK pathway.
Casnumber
3002056-30-3
Formula
C22H18F2N4O5S
Mw
488.46
Psmiles
CC1=C(C(=O)OC2=C1C=CC(=C2)OC3=C(C=CC=N3)F)CC4=C(C(=NC=C4)NS(=O)(=O)NC)F
Purity
>98.5%
NST-628

NST-628

$839.50 USD