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NVP-2

NVP-2

Regular price $287.50 USD
Sale price Regular price

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
NVP-2 is an effective and selective ATP competitive cyclin-dependent kinase 9 (CDK9) probe that inhibits CDK9/CycT activity.IC50 The value is 0.514 nM. NVP-2 has inhibitory effects on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases, which IC50 The values are 0.584 μM, 0.706 μM, and 0.605 μM, respectively. NVP-2 induces apoptosis.
Casnumber
1263373-43-8
Formula
C27H37ClN6O2
Mw
513.07
Psmiles
COCC(C)NC1CCC(CC1)NC2=CC(=C(Cl)C=N2)C3=NC(=CC=C3)NCC4(CCOCC4)C#N
Purity
>99%
Solubility
DMSO ≥ 60 mg/mL
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