O4I3

Vendor: Abmole

Type: Biochemical Assay

SKU: M54719

$57.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
O4I3 is a potent and selective inhibitor of the KDM5A (JARID1A) isoform of H3K4 demethylase, with an IC50 value of 0.15 nM.O4I3 effectively induces OCT4 expression and enhances OSKM-induced pluripotent stem cell reprogramming efficiency (50 nM) of human primary fibroblasts by preventing KDM5A from interfering with the enrichment of H3K4Me3 on the OCT4 promoter. iPSC) reprogramming efficiency (50 nM).
Casnumber
88965-00-8
Formula
C15H14N2
Mw
222.29
Psmiles
CC1=CC=C(C=C1)C2=CN3C=C(C=CC3=N2)C
Purity
>99.0%
Solubility
DMSO 2 mg/mL
O4I3

O4I3

$57.50 USD