Onametostat (JNJ-64619178)

Vendor: Abmole

Type: Molecular

SKU: M13371

$402.50 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Onametostat (JNJ-64619178) is a highly selective, orally active, pseudo-irreversible protein arginine methyltransferase 5 (PRMT5) inhibitor (PRMT5-MEP-50, IC50=0.14 nM).Onametostat does not covalently bind to PRMT5, but has a long interaction time. It has good pharmacokinetic properties as well as safety profile.
Casnumber
2086772-26-9
Formula
C22H23BrN6O2
Mw
483.36
Psmiles
C1C(C(C(C1N2C=CC3=C(N=CN=C32)N)O)O)CCC4=CC5=NC(=C(C=C5C=C4)Br)N
Purity
>99%
Solubility
DMSO ≥ 60 mg/mL
Onametostat (JNJ-64619178)

Onametostat (JNJ-64619178)

$402.50 USD