Onvansertib

Vendor: Abmole

Type: Molecular

SKU: M13718

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$120.75 USD
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For research use only — not intended for clinical or diagnostic purposes.
Onvansertib

Onvansertib

$120.75 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
Onvansertib (PCM-075, NMS-1286937, NMS-P937) is a first-in-class, third-generation, oral, highly selective PLK1 inhibitor that induces tumor cell arrest in the G2/M phase and triggers apoptosis. It has a median IC50=136nM against a variety of CRC cell lines and inhibits xenograft models such as HT-29, HCT-116, and Colo-205 well.
Casnumber
1034616-18-6
Formula
C24H27F3N8O3
Mw
532.52
Psmiles
CN1CCN(CC1)C2=CC=C(OC(F)(F)F)C(=C2)NC3=NC4=C(CCC5=C4[N](CCO)N=C5C(N)=O)C=N3
Purity
>99%
Solubility
DMSO 21 mg/mL
Target synonyms
PCM-075; NMS-1286937; NMS-P937
Technical documents

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