ONX-0914

Vendor: Abmole

Type: Molecular

SKU: M2071

Explore specifications & documents
$272.55 USD
Shipping calculated at checkout.

Documents

Coa

Available in stock (500)

Request a quotation
  • Customs clearance fees may apply
  • Worldwide shipping available.
For research use only — not intended for clinical or diagnostic purposes.
ONX-0914

ONX-0914

$272.55 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
Onx-0914 (PR-957) is a selective inhibitor of low molecular weight polypeptide 7 (LMP7), a chymotrypsin subunit of the immune proteasome. Onx-0914 blocks cytokine production and reduces the progression of experimental arthritis. Onx-0914 is a non-competitive irreversible inhibitor of mycobacterium proteasome (Ki=5.2 μM). Onx-0914 activates latent HIV-1 through HF-1-mediated p-TEFb activation.
Casnumber
960374-59-8
Formula
C31H40N4O7
Mw
580.67
Psmiles
CC(C(=O)NC(CC1=CC=C(C=C1)OC)C(=O)NC(CC2=CC=CC=C2)C(=O)C3(CO3)C)NC(=O)CN4CCOCC4
Purity
>99%
Solubility
DMSO 40 mg/mL
Target synonyms
PR-957
Technical documents

Documents

Coa

A PARTNER IN YOUR RESEARCH

More time for discovery. Less time sourcing.

Bring your laboratory requirements together with scientific advice, global sourcing and dedicated procurement support.

Explore our services

Starting a new laboratory?

Plan your laboratory with our New-Lab programme.

Discover New-Lab