Ophiopogonin D'

Vendor: Abmole

Type: Molecular

SKU: M8488

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$552.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Ophiopogonin D'

Ophiopogonin D'

$552.00 USD

THE SCIENCE, IN DETAIL

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Specifications
Bioactivity
Ophiopogonin D', isolated from the tuber of Ophiopogon japonicus, is a rare naturally occurring C29 steroid glycoside. Ophiopogonin D' has cytotoxic activity against two human tumor cell lines mG-63 and SNU387. Ophiopogonin D' can induce necrotic apoptosis of prostate cancer LNCaP cells by activating RIPK1. IC50 were 3.09 μM and 3.63 μM, respectively. SIRT1 is activated in a dose-dependent manner by Ophiopogonin D'.
Casnumber
65604-80-0
Formula
C44H70O16
Mw
855.02
Psmiles
C[C@@H]1CC[C@]2(OC1)[C@@H](C)[C@H]3[C@H](C[C@@H]4[C@]3(C)CC[C@H]5[C@H]4CC=C6[C@]5(C)CC[C@H](O[C@H]7[C@H](O[C@H]8[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O8)[C@@H](O[C@H]9[C@H](O)[C@@H](O)[C@H](O)CO9)[C@H](O)[C@@H](CO)O7)C6)O2
Purity
≥99.0%
Solubility
DMSO 10 mg/mL
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