ORC2 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES9281
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Nucleus.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
4999
Human swiss prot no
Q13416
Immunogen
Synthesized peptide derived from human protein . at AA range: 180-260
Isotype
IgG
Observed band
63kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-me
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Product Citations
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More Info
More Info
ORC2 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
