p107 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES7012
Regular price
$148.00 USD
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Regular price
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
IF;ELISA
Cellular localization
Nucleus .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
5933
Human swiss prot no
P28749
Immunogen
The antiserum was produced against synthesized peptide derived from human RBL1. AA range:335-384
Isotype
IgG
Product weight
0.005kg
Reactivity
Human;Mouse
Recommended dilutions
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms hav
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Product Citations
More Info
More Info
p107 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
