p18 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES3099
Regular price
$148.00 USD
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Regular price
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
nucleus,cytoplasm,cytosol,
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
1031
Human swiss prot no
P42773
Immunogen
The antiserum was produced against synthesized peptide derived from human p18 INK. AA range:111-160
Isotype
IgG
Observed band
18kD
Product weight
0.005kg
Reactivity
Human;Mouse;Monkey
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008],
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More Info
More Info
p18 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
