p63 (phospho Ser455) rabbit pAb

Name: p63 (phospho Ser455) rabbit pAb
Brand: ELK Biotechnology
Price: 148.0 USD
Availability: InStock

Vendor: ELK Biotechnology

SKU: ES1487

$148.00 USD

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications

WB;IHC;IF;ELISA

Cellular localization

Nucleus .

Clonality

Polyclonal

Concentration

1 mg/ml

Geneid human

8626

Human swiss prot no

Q9H3D4

Immunogen

The antiserum was produced against synthesized peptide derived from human p63 around the phosphorylation site of Ser455. AA range:421-470

Isotype

IgG

Observed band

70kD

Product weight

0.005kg

Reactivity

Human;Rat;Mouse;

Recommended dilutions

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Source

Rabbit

Storage

-20°C/1 year

Background

tumor protein p63(TP63) Homo sapiens This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrim

p63 (phospho Ser455) rabbit pAb

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