Patched rabbit pAb

Name: Patched rabbit pAb
Brand: ELK Biotechnology
Price: 148.0 USD
Availability: InStock

Vendor: ELK Biotechnology

SKU: ES6881

$148.00 USD

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications

WB;IHC;IF;ELISA

Cellular localization

Cell membrane ; Multi-pass membrane protein .

Clonality

Polyclonal

Concentration

1 mg/ml

Geneid human

5727

Human swiss prot no

Q13635

Immunogen

The antiserum was produced against synthesized peptide derived from human Patched. AA range:1-50

Isotype

IgG

Observed band

160kD

Product weight

0.005kg

Reactivity

Human;Mouse

Recommended dilutions

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Source

Rabbit

Storage

-20°C/1 year

Background

This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq, Jul 2008],

Patched rabbit pAb

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