PDGF-B rabbit pAb
Vendor: ELK Biotechnology
SKU: ES6530
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
IF;WB;IHC;ELISA
Cellular localization
Secreted. Released by platelets upon wounding.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
5155
Human swiss prot no
P01127
Immunogen
The antiserum was produced against synthesized peptide derived from human PDGFB. AA range:16-65
Isotype
IgG
Observed band
27kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
platelet derived growth factor subunit B(PDGFB) Homo sapiens This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
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Product Citations
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More Info
More Info
PDGF-B rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
