Pemigatinib

Vendor: Abmole

Type: Molecular

SKU: M9596

$207.00 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Pemigatinib (INCB054828) is an orally effective, selective FGFR inhibitor with IC50 values of 0.4 nM, 0.5 nM, 1.2 nM, and 30 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.Pemigatinib exhibited anti-tumor activity in mouse xenograft models with FGFR1, FGFR2, or FGFR3-altered human tumors in a mouse xenograft model exhibiting antitumor activity.
Casnumber
1513857-77-6
Formula
C24H27F2N5O4
Mw
487.5
Psmiles
CCN1C(=O)N(CC2=C1C3=C([NH]C(=C3)CN4CCOCC4)N=C2)C5=C(F)C(=CC(=C5F)OC)OC
Purity
99.79%
Solubility
DMSO ≥ 32 mg/mL
Target synonyms
INCB054828
Pemigatinib

Pemigatinib

$207.00 USD