Pexmetinib (ARRY-614)

Vendor: Abmole

Type: Molecular

SKU: M5873

$235.75 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Pexmetinib (ARRY-614) is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with IC50 of 4 nM/18 nM in a HEK-293 cell line. Phase 1.
Casnumber
945614-12-0
Formula
C31H33FN6O3
Mw
556.63
Psmiles
CC1=CC=C(C=C1)[N]2N=C(C=C2NC(=O)NCC3=C(OC4=CC5=C(C=C4)[N](CCO)N=C5)C=CC(=C3)F)C(C)(C)C
Purity
>98%
Solubility
100 mg/mL in DMSO
Target synonyms
ARRY-614
Pexmetinib (ARRY-614)

Pexmetinib (ARRY-614)

$235.75 USD