תמונת ברירת מחדל

Pimitespib

Vendor: Abmole

Type: Molecular

SKU: M20676

$851.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
TAS-116 is a novel, small-molecule HSP90 inhibitor which inhibits geldanamycin-FITC binding to HSP90 proteins with Ki values of 34.7 nmol/L, 21.3 nmol/L, >50,000 nmol/L, and >50,000 nmol/L for HSP90α, HSP90β, GRP94, and TRAP1, respectively. Furthermore, TAS-116 does not inhibit other ATPases such as HSP70 (IC50 >200 μmol/L).
Casnumber
1260533-36-5
Formula
C25H26N8O
Mw
454.53
Psmiles
CCC1=C(C=CC(=C1)C(N)=O)[N]2N=C(C(C)C)C3=C(C=CN=C23)[N]4C=NC(=C4)C5=C[N](C)N=C5
Purity
>99%
Solubility
DMSO 91 mg/mL
Target synonyms
TAS-116
תמונת ברירת מחדל

Pimitespib

$851.00 USD