PINK1 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES10983
Regular price
$148.00 USD
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Regular price
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Mitochondrion outer membrane ; Single-pass membrane protein . Mitochondrion inner membrane ; Single-pass membrane protein . Cytoplasm, cytosol . Localizes mostly in mitochondrion and the two smaller proteolytic processed fragments localize mainly in cytosol (PubMed:19229105). When mitochondria lose mitochondrial membrane potential following damage, PINK1 import is arrested, which induces its accumulation in the outer mitochondrial membrane, where it acquires kinase activity (PubMed:18957282). .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
65018
Human swiss prot no
Q9BXM7
Immunogen
Synthesized peptide derived from part region of human protein
Isotype
IgG
Observed band
63kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq, Jul 2008],
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More Info
More Info
PINK1 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per

