PKA IIβ reg rabbit pAb
Vendor: ELK Biotechnology
SKU: ES3217
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Cytoplasm . Cell membrane . Colocalizes with PJA2 in the cytoplasm and at the cell membrane.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
5577
Human swiss prot no
P31323
Immunogen
The antiserum was produced against synthesized peptide derived from human PKA-R2 beta. AA range:79-128
Isotype
IgG
Observed band
46kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activ
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More Info
More Info
PKA IIβ reg rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
