PKC (phospho Thr497) rabbit pAb
Vendor: ELK Biotechnology
SKU: ES6766
Regular price
$148.00 USD
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Regular price
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Cytoplasm . Cell membrane ; Peripheral membrane protein . Mitochondrion membrane ; Peripheral membrane protein . Nucleus .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
5578/5579/5580/5581/5582/5583/5588/5590
Human swiss prot no
P17252/P05771/Q05655/Q02156/P05129/P24723/Q04759/Q05513
Immunogen
The antiserum was produced against synthesized peptide derived from human PKC-pan around the phosphorylation site of Thr497. AA range:623-672
Isotype
IgG
Observed band
83kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2
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More Info
PKC (phospho Thr497) rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
