PLOD2 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES11324
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
5352
Human swiss prot no
O00469
Immunogen
Synthesized peptide derived from human protein . at AA range: 600-680
Isotype
IgG
Observed band
81kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
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More Info
PLOD2 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
