PP2B-Aα rabbit pAb

Name: PP2B-Aα rabbit pAb
Brand: ELK Biotechnology
Price: 148.0 USD
Availability: InStock

Vendor: ELK Biotechnology

SKU: ES20264

$148.00 USD

Shipping calculated at checkout.

Documents

Manuals

Supplier image

Available in stock (100)

Customs clearance fees may apply
Worldwide shipping available.

For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications

WB;IHC

Cellular localization

Cytoplasm . Cell membrane ; Peripheral membrane protein . Cell membrane, sarcolemma . Cytoplasm, myofibril, sarcomere, Z line . Cell projection, dendritic spine . Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle (By similarity). Recruited to the cell membrane by scaffold protein AKAP5 following L-type Ca(2+)-channel activation (PubMed:22343722). .

Clonality

Polyclonal

Concentration

1 mg/ml

Geneid human

5530

Human swiss prot no

Q08209

Immunogen

Synthesized peptide derived from human PP2B-Aα

Isotype

IgG

Product weight

0.005kg

Reactivity

Human;Mouse;Rat

Recommended dilutions

WB 1:500-2000;IHC-p 1:50-300

Source

Rabbit

Storage

-20°C/1 year

Background

catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,cofactor:Binds 1 Fe(3+) ion per subunit.,cofactor:Binds 1 zinc ion per subunit.,function:Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates HSPB1 and SSH1.,online information:Calcineurin entry,similarity:Belongs to the PPP phosphatase family.,similarity:Belongs to the PPP phosphatase family. PP-2B subfamily.,subcellular location:Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle.,subunit:Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity. Interacts with TORC2/CRTC2, MYOZ1, MYOZ2 and MYOZ3.,

PP2B-Aα rabbit pAb

Documents

Product Overview

Background

Documents

Documents

Product Citations

More Info