Propargyl-PEG1-acid

Vendor: Abmole

Type: Molecular

SKU: M58639

$17.25 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Propargyl-PEG1-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-CRBN PROTACs. BTK-CRBN PROTACs act as stoichiometric degraders, resulting in degradation of BTK protein. Degradation of BTK is a result of cereblon E3 ligases family recruitment. Propargyl-PEG1-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Casnumber
55683-37-9
Formula
C6H8O3
Mw
128.13
Psmiles
C#CCOCCC(=O)O
Purity
≥97.0%
Solubility
DMSO 45 mg/mL
Target synonyms
3-(2-Propynyloxy)propanoic acid
Propargyl-PEG1-acid

Propargyl-PEG1-acid

$17.25 USD