PTC299

Vendor: Abmole

Type: Molecular

SKU: M28065

$540.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
PTC299 is an orally active inhibitor of VEGFA mRNA translation that selectively inhibits VEGF protein synthesis at the post-transcriptional level. PTC299 is also a potent inhibitor of dihydroorotate dehydrogenase (DHODH). PTC299 shows good oral bioavailability and lack of off-target kinase inhibition and myelosuppression. PTC299 can be useful for the research of hematologic malignancies.
Casnumber
1256565-36-2
Formula
C25H20Cl2N2O3
Mw
467.34
Psmiles
COC1=CC=C(C=C1)C2N(CCC3=C2[NH]C4=C3C=C(Cl)C=C4)C(=O)OC5=CC=C(Cl)C=C5
Purity
≥99.0%
Solubility
DMSO 50 mg/mL (ultrasonic)
PTC299

PTC299

$540.50 USD