PTPα rabbit pAb
Vendor: ELK Biotechnology
SKU: ES6939
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA;IHC
Cellular localization
Cell membrane ; Single-pass type I membrane protein . Cell junction, focal adhesion . Localizes to focal adhesion sites following integrin engagement. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
5786
Human swiss prot no
P18433
Immunogen
Synthesized peptide derived from PTPα . at AA range: 730-810
Isotype
IgG
Observed band
90kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008],
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More Info
More Info
PTPα rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
