PTPRF rabbit pAb
Vendor: ELK Biotechnology
SKU: ES11149
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Membrane; Single-pass type I membrane protein.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
5792
Human swiss prot no
P10586
Immunogen
Synthesized peptide derived from part region of human protein
Isotype
IgG
Observed band
209kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pat
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Product Citations
Product Citations
More Info
More Info
PTPRF rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per

