PU02

Vendor: Abmole

Type: Molecular

SKU: M25487

$132.25 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
PU02 (NMMP) is a potent and selective negative allosteric modulator (NAM) of 5-HT3 receptor, displaying IC50 values of ~1 μM at 5-HT(3)Rs and substantially lower activities at other Cys-loop receptors. PU02 inhibits the proliferation of hepatocellular carcinoma (HepG2) cells associated with G2/M phase cell cycle arrest, and reduced cyclin-dependent kinase (CDK) 4 and cyclin B1/D1 levels.
Casnumber
313984-77-9
Formula
C16H12N4S
Mw
292.36
Psmiles
C1=CC=C2C(=C1)C=CC=C2CSC3=NC=NC4=C3NC=N4
Purity
>99.0%
Solubility
DMSO >100 mg/mL
Target synonyms
NMMP
PU02

PU02

$132.25 USD